Understanding Nasal Polyps and Type 2 Inflammation

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Legal Notice

Last Modified (April 2019)

This website (“Website”) is provided to you under these "Terms of Use" and any amendments or supplements to them (collectively referred to as this "Agreement") that may be posted by Genzyme Corporation or one of its affiliated companies (collectively, “Site Owner,” "we", "us") from time to time. Your use of this Website, or any other services or content provided through the Website shall be deemed to constitute your consent to be legally bound by the terms and conditions of the Agreement, which shall be enforceable in the same way as if you had signed the Agreement. If you are not willing to accept the terms and conditions in the Agreement, we ask that you not access or use the Website.

WEBSITE INTENDED AUDIENCE

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INFORMATION DISCLAIMER

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OWNERSHIP

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To the extent personal data is obtained through the website, Genzyme Corporation is data controller for the processing of that personal data.

Genzyme Corporation:
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Massachusetts 02142
Tel.: +1 (617) 252-7500

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MODIFICATIONS TO THESE TERMS

We may make changes to the Terms of Use from time to time in our sole discretion, by updating these Terms of Use on this Website, and specifying the effective date of the new version of the Terms of Use. The “Last Modified” date at the top of these Terms of Use will indicate when the latest changes were made. Your continued use of the Website following the posting of a new version of the Terms of Use constitutes your acceptance of any such changes. Accordingly, whenever you visit this Website, you should check to see if a new version of the Agreement has been posted.

CONTACT INFORMATION

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SEVERABILITY OF AGREEMENT

Should any part or provision of these Terms of Use be held unlawful, void, invalid, or unenforceable that portion shall be deemed severable from these Terms of Use and shall not affect the validity and enforceability of any remaining provisions.

SURVIVAL

All Sections shall survive the termination of the right to use the Website.

APPLICABLE LAW AND JURISDICTION

The information on the Website is intended for audiences globally. The Agreement and the resolution of any dispute related to the Agreement, the Website, or items you purchase through the Website, and any non-contractual obligations arising out of or in connection with these Terms of Use, shall be governed by and construed in accordance with the laws of the Commonwealth of Massachusetts in the United States of America and you agree to submit to the personal and exclusive jurisdiction of such courts.

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Heffler, Enrico, et al. “The Severe Asthma Network in Italy: Findings and Perspectives.” The Journal of Allergy and Clinical Immunology: In Practice 7.5 (2019): 1462-1468.
Dharmage, Shyamali C., Jennifer Perret, and Adnan Custovic. Epidemiology of asthma in children and adults. Frontiers in paediatrics. 7 (2019): 246.
Network GA. The Global Asthma Report, Auckland, New Zealand. (2018).
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Robinson D, Humbert M, Buhl R, et al. Revisiting type 2-high and type 2-low airway inflammation in asthma: current knowledge and therapeutic implications. Clin Exp Allergy. 2017: 47(2): 161-175.
Fahy JV. Type 2 inflammation in asthma — present in most, absent in many. Nat Rev lmmunol. 2015;15(1):57-65.
Global Initiative for Asthma (GINA). Pocket Guide for Asthma Management and Prevention. 2020. Available at: https://ginasthma.org/wp-content/uploads/2020/04/Main-pocket-guide_2020_04_03-final-wms.pdf. Last Accessed April 2020.
Behmanesh F, et al. Evaluation of anxiety and depression in mothers of children with asthma. Electron Physician. 2017:9(12);6058-6062.
Asthma and Allergy Foundation of America. My Life with Asthma Report. Available at http://www.aafa.org/my-life-with-asthma-report/. Last accessed October 2018.
Asthma and Allergy Foundation of America. My Life with Asthma Survey Overview. Available at: http://www.aafa.org/media/1684/my-life-with-asthma-in-2017-survey-findings-report.pdf. Last accessed October 2018.
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Gandhi NA, Bennett BL, Graham NM, et al. Targeting key proximal drivers of type 2 inflammation in disease. Nat Rev Drug Discov. 2016;15(1):35-50.
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Amelink M, de Groot JC, de Nijs SB, Lutter R, Zwinderman AH, Sterk PJ, ten Brinke A, Bel EH. Severe adult-onset asthma: a distinct phenotype. Journal of allergy and clinical immunology. 2013 Aug 1;132(2):336-41.
Stevens WW, Peters AT, Hirsch AG, Nordberg CM, Schwartz BS, Mercer DG, Mahdavinia M, Grammer LC, Hulse KE, Kern RC, Avila P. Clinical characteristics of patients with chronic rhinosinusitis with nasal polyps, asthma, and aspirin-exacerbated respiratory disease. The Journal of Allergy and Clinical Immunology: In Practice. 2017 Jul 1;5(4):1061-70.
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Dietz de Loos DA, Hopkins C, Fokkens WJ. Symptoms in chronic rhinosinusitis with and without nasal polyps. Laryngoscope. 2013;123(1):57-63.
SNOT-20 Copyright © 1996 by Jay F. Piccirillo, M.D., Washington University School of Medicine, St. Louis, Missouri SNOT-22 Developed from modification of SNOT-20 by National Comparative Audit of Surgery for Nasal Polyposis and Rhinosinusitis Royal College of Surgeons of England.
Bachert C, Gevaert E. Advances in rhinitis and rhinosinusitis in 2015. J Allergy Clin Immunol. 2016;138(5):1277-1283.
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Khan A, Vandeplas G, Huynh TMT, et al. The Global Allergy and Asthma European Network (GALEN rhinosinusitis cohort: a large European cross-sectional study of chronic rhinosinusitis patients with and without nasal polyps. Rhinology. 2019;57(1):32-42.
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Privacy Policy

WHY THIS DOCUMENT?

As part of its day to day operation, SANOFI provides access to a variety of tools and resources which are destined to provide information to all the individuals with whom it has business interactions with (patients and their relatives, participants to clinical trials, healthcare professionals, users of products and services, workers, etc.) regarding its activities.

Such tools and resources may be provided in various formats, including, more specifically in electronic format and by means of online electronic communications, including the website available at www.sanofi.com and any other website made available by SANOFI and to which this policy applies (hereinafter together the “Website”). In order to be able to provide them, SANOFI may need to collect and process Personal Data (as defined below) of their users.

SANOFI is fully committed to the protection of Personal Data and intends to provide you with all relevant information regarding the way in which SANOFI processes your Personal Data on the Website.

You will therefore find below all relevant information regarding the processing of Personal Data conducted on this Website. Please note that the content of this Website Privacy Policy may change from time to time, for instance in case of evolution of our processes or as a result of applicable law. Should these changes be objectively substantial and affect your rights or our obligations pertaining to the protection of Your Personal Data (and insofar as we have a means to contact you), we will notify you of the update by adequate means based on the information we may have collected.

However, we advise you to visit the page of this Website Privacy Policy regularly to verify any updates.

WHO IS RESPONSIBLE FOR THE PROCESSING OF PERSONAL DATA ON THIS WEBSITE (THE CONTROLLER)?

Genzyme Corporation is responsible for the processing of Personal Data of individuals using this website and therefore acts as the Controller:

Genzyme Corporation
50 Binney Street,
Cambridge, Massachusetts 02142
Tel.: + 1 (617) 252-7500

REMINDER: WHAT IS PERSONAL DATA & PROCESSING?

For the purposes of this Website Privacy Policy, Personal Data is any information relating to an identified or identifiable natural person, for all data processing carried out in the framework of its business and activities.

To make things clear, it is any information that relates to an individual. Such Personal Data can take the form of:

Basic identification information such as your name or date of birth;
Information that can be attributed to you directly or indirectly – such as a post on a social media;
Information which can be associated to you or your device such as, for instance, an IP address (i.e. the network address of your machine);
Etc.

In this respect, the notion of “processing” designates any action that is undertaken on your Personal Data such as, for instance:

Collection;
Storage;
Access;
Analysis;
Deletion;
Etc.

WHAT PERSONAL DATA DOES THIS WEBSITE COLLECT?

When operating, this Website may collect the following categories of Personal Data:

Connection data: any information regarding your connection and access to this Website (e.g. type of machine and browser used, timestamp of your connection, IP address, pages visited, etc.), browsing history
Location data: information that may be provided by your machine and browser about your location if you allow such information to be shared with Sanofi

Data relating to and data which may be collected by cookies: for more information about cookies, please click here to view our cookies policy (the cookies policy can be accessed by clicking the appropriate tab found here.) In addition, this website embeds poll functionality which asks survey questions regarding health conditions. The responses to the survey questions are collected anonymously and aggregated with other responses in order to show collective results. The poll is multiple-choice with no option for free text.

FOR WHAT PURPOSES DOES THIS WEBSITE COLLECT PERSONAL DATA?

Any processing of Personal Data must be implemented for a defined purpose. In this respect, the collection and processing of Personal Data on this Website is conducted for the following purposes:

To personalize your browsing experience: when using our services; ensure that our services are presented in the way that best suits you; understand your professional and personal interests in our content, products and services or other content and adapt our content to your needs and preferences; present you products and offers tailored to you.
To improve our products and services: identify usage trends and develop new products and services; understand how you and your device interacts with our services; track and respond to safety concerns; determine the effectiveness of our promotional campaigns, conduct surveys.

ON WHAT GROUNDS DOES THIS WEBSITE PROCESS YOUR PERSONAL DATA?

For the purposes of this Website, your Personal Data is only processed on the basis of:

your prior CONSENT: where you have clearly expressed your approval of SANOFI’s processing of your Personal Data. In practice, this will generally mean that SANOFI will ask you to sign a document, or to fill-in an online “opt-in” form or to follow any relevant procedure to allow you to be fully informed and then either clearly accept or refuse the envisaged Personal Data processing. By navigating this Website and, if relevant, consenting to the processing of your Personal Data using cookies (as per our cookies policy).
a contractual relationship between you and SANOFI: in such case, the processing of your Personal Data is generally necessary to the execution or the performance of the contract; this means that if you do not wish SANOFI to process your Personal Data in that context, SANOFI may or will be obliged to refuse to enter into such contract with you or will not be able to provide the products or services covered in this contract.
the “legitimate interest” of SANOFI in the sense of applicable data protection law. In such a case, SANOFI shall consider your fundamental rights and interests in determining whether the processing is legitimate and lawful.

HOW LONG IS THE PERSONAL DATA COLLECTED ON THIS WEBSITE RETAINED?

The Personal Data collected on this Website will be retained for the following periods, depending on the categories of Personal Data processed

Connection data: Session duration
Location data: Two years

data relating to and data which may be collected by cookies: Please see the cookies policy. The cookies policy can be accessed by clicking the appropriate tab found here.

WHO HAS ACCESS TO PERSONAL DATA

SANOFI may transfer your Personal Data both internally (i.e. to other SANOFI entities) and/or externally to third party service providers for the purposes outlined above.

Where such internal or external transfer of Personal Data implies the transfer of your Personal Data to a country providing a lower level of protection to Personal Data than generally afforded in your jurisdiction, SANOFI will ensure that a sufficient level of protection is provided to your Personal Data by implementing adequate safeguards such as the European Standard Contractual Clauses, the SANOFI Binding Corporate Rules or asking for your prior explicit consent.

YOUR RIGHTS: SANOFI WILL ENSURE THAT YOU CAN EXERCISE YOUR RIGHTS PERTAINING TO YOUR PERSONAL DATA

You can exercise your rights as provided by applicable data protection laws.

To that end, SANOFI informs you that you are entitled:

to have access upon simple request to your Personal Data – in which case you may receive a copy of such data (if requested), unless such data is made directly available to you, for instance within your personal account;
to obtain a rectification of your Personal Data should your Personal Data be inaccurate, incomplete or obsolete;
to obtain the deletion of your Personal Data in the situations set forth by applicable data protection law (‘right to be forgotten’);
to withdraw your consent to the processing of Persona Data processing without affecting the lawfulness of processing, where your Personal Data has been collected and processed on the basis of your consent;
to object to the processing of your Personal Data, where your Personal Data has been collected and processed on the basis of legitimate interests of SANOFI, in which case you will need to justify your request by explaining to us your particular situation;
to request a limitation of the processing of Personal Data processing in the situations set forth by applicable data protection law;
to receive your Personal Data for transmission from SANOFI to a third-party or to have your Personal Data directly transferred by SANOFI to the third-party of your choice, where technically feasible (data portability right allowed only where the processing is based on your consent)

If you would like to exercise any of these rights, please contact us as described in the “How to Contact Us” section below and we will take necessary steps to respond as soon as possible.

You may also file a complaint before a competent data protection authority regarding the processing of your Personal Data. While we suggest that you contact us beforehand, if you wish to exercise this right, you should contact directly the competent data protection authority.

HOW TO CONTACT US

SANOFI welcomes any questions or comments you may have regarding this Website Privacy Policy or its implementation. You can send any request pertaining to SANOFI’s use of your Personal Data to our Data Protection Officer at the following email address: privacy-office-global@sanofi.com.

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Sanofi Genzyme and Regeneron do not review the information contained on this website and/or database for content, accuracy, or completeness. Use of and access to this information is subject to the terms, limitations, and conditions set by the website and/or database producer. Sanofi Genzyme and Regeneron make no representation as to the accuracy or any other aspect of the information contained on such website and/or database, nor does Sanofi Genzyme and Regeneron necessarily endorse such website and/or database.

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References

Emmerman et al. Prospective Multicenter Study of Relapse Following Treatment for Acute Asthma Among Adults Presenting to the Emergency Department. CHEST. 1999. 115(4):919-27
Price et al. Types, frequency and impact of asthma triggers on patients’ lives: a quantitative study in five European countries. J Asthma. 2014. 51(2):127-35
Chipps et al. Key findings and clinical implications from The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study. J Allergy Clin Immunol. 2012 Aug;130(2):332-42
Price et al. Asthma control and management in 8,000 European patients: the Recognise Asthma and Link to Symptom and Experience (REALISE) survey. NPJ Prim Care Respir Med. 2014. 12(24):14009
Sastre et al. Insights, attitudes, and perceptions about asthma and its treatment: a multinational survey of patients from Europe and Canada. World Allergy Organ J. 2016. 4(9):13
Global Initiative for Asthma (GINA). Pocket Guide for Asthma Management and Prevention. 2019. Available at: https://ginasthma.org/2018-pocket-guide-for-asthma-management-and-prevention/. Last Accessed August 2019
Fletcher & Hiles. Continuing discrepancy between patient perception of asthma control and real-world symptoms: a quantitative online survey of 1,083 adults with asthma from the UK. Prim Care Respir J. 2013. 22(4): 431-438
McDonald et al. Health-related quality of life burden in severe asthma. Med J Aust. 2018. 209(S2): S28-S33

Nasal polyps make me feel like I’m being smothered.”

See what science has revealed

Nasal polyps make me feel like I’m being smothered.”

See what science has revealed

With nasal polyps,
I feel like
my nose is
always running.”

Get a clearer
understanding

The facts
about surgery
and steroids.

Steroids can come
with significant
side effects.

Nasal polyps
often come back
after surgery.

Nasal polyps
make me feel like
I’m drowning
in a sea of tissues.”

Moving the future of asthma forward, together

#TheNextBreath

Nasal polyps make me feel like I’m being smothered.”

See what science has revealed

Nasal polyps make me feel like I’m being smothered.”

See what science has revealed

With nasal polyps, I feel like my nose is always running.”

Get a clearer understanding

The facts about surgery and steroids.

Steroids can come with significant side effects.

Nasal polyps often come back after surgery.

Nasal polyps make me feel like I’m drowning in a sea of tissues.”

Moving the future of asthma forward, together

#TheNextBreath

With nasal polyps,
I feel like
my nose is
always running.”

Get a clearer
understanding

The facts
about surgery
and steroids.

Steroids can come
with significant
side effects.

Nasal polyps
often come back
after surgery.

Nasal polyps
make me feel like
I’m drowning
in a sea of tissues.”